Site Manager | San Francisco

About the role

You own the end-to-end operational integrity of the Plasmidsaurus San Francisco site on a daily basis. You ensure the laboratory and office environments run with precision so scientists can focus exclusively on sequencing and discovery. You serve as the connective tissue between facilities, procurement, IT, and laboratory leadership, translating strategic goals into reliable local execution. You notice what needs fixing the moment it appears and take immediate ownership to resolve it. You create a workplace that feels organized, predictable, and easy to navigate for every person who walks through the door. You partner with procurement as a trusted collaborator to keep supplies flowing and remove bottlenecks before they impact sequencing. You represent the site professionally to candidates, customers, vendors, and visitors, ensuring every interaction reflects the Plasmidsaurus standard of excellence.

Key facts

What you'll do

Own the day-to-day operation of the SF laboratory, ensuring it is organized, well-maintained, fully stocked, and ready to support uninterrupted sequencing operations.

Manage laboratory organization and operational readiness so workflows remain efficient and compliant at all times.

Manage laboratory inventory and consumable stock levels in partnership with Procurement to prevent shortages and reduce waste.

Coordinate deliveries and receive shipments, verifying accuracy, logging materials, and resolving discrepancies promptly.

Coordinate equipment acquisition, installation, preventative maintenance, and repairs to minimize downtime and ensure peak performance.

Maintain organized, efficient laboratory workspaces that support safety, clarity, and standardized procedures.

Support laboratory budgeting and local operational spending through careful tracking and vendor management.

Partner with laboratory teams to identify and resolve operational issues before they disrupt sequencing work.

Own local safety execution so the SF laboratory remains safe, organized, and inspection-ready for internal and external reviews.

Execute BSL2 safety procedures, inspections, and documentation, including setup and oversight of a BSL2 room for potentially infectious material.

Coordinate EH&S activities, including scheduling trainings and documenting chemical and hazardous material inventory with meticulous accuracy.

Ensure safety equipment is maintained, tested, and accessible to meet regulatory standards and protect all personnel.

Partner with the Operations & Facilities teams to implement new compliance initiatives and close any identified gaps.

Support laboratory teams during inspections or audits by providing clear documentation and operational evidence.

Own the day-to-day operation of our San Francisco headquarters, creating a workplace that is organized, welcoming, and enables employees to do their best work.

Manage office supplies and common spaces to maintain a clean, functional, and professional environment for all staff.

Coordinate office vendors including cleaning, kitchen, maintenance, security, and related services to ensure consistent service quality.

Serve as the primary contact for the landlord and day-to-day facilities issues, handling escalations with clarity and urgency.

Manage incoming mail and deliveries, ensuring sensitive materials are handled confidentially and routed appropriately.

Welcome candidates, customers, and visitors and facilitate their visits with a polished, professional experience.

Help coordinate onsite interviews and meeting logistics, ensuring guests know their way around the building and have what they need.

Organize SF-based employee events and community-building activities that strengthen culture and engagement across the team.

Coordinate light IT logistics such as workstation setup, accessories, and equipment inventory in partnership with the IT team to maintain productivity.

Own the overall operational health of the SF site by coordinating vendors, identifying issues before they become problems, and continuously improving site functions as the company scales.

Coordinate local vendors and contractors to ensure timely, high-quality execution of services and projects.

Escalate larger facilities projects to the Operations & Facilities team with clear documentation and impact analysis.

Partner with Operations, Facilities, Procurement, IT, and laboratory leadership to keep the site running smoothly and align on priorities.

Continuously improve local workflows, communication, and site operations through feedback, data, and experimentation.

Requirements

You are legally authorized to work in the United States without sponsorship.

You are based in or are willing to relocate to San Francisco, California, and you can commute reliably to our headquarters.

You have a demonstrated history of managing complex operational environments, including laboratories, offices, and vendor relationships.

You are comfortable working in a fast-paced, rapidly scaling startup where priorities can shift quickly and adaptability is essential.

You have strong written and verbal communication skills and can represent Plasmidsaurus professionally to internal and external stakeholders.

You are highly organized, detail-oriented, and capable of managing multiple concurrent projects with competing deadlines.

You understand and can execute BSL2 safety protocols, including documentation, training oversight, and regulatory compliance.

You are comfortable using standard software tools for communication, coordination, and basic data tracking.

Nice to have

Experience managing sequencing laboratory operations or a high-throughput scientific environment.

Familiarity with procurement systems and inventory management best practices.

Background in coordinating candidate visits, onsite interviews, and workplace logistics for growing teams.

Experience supporting compliance, audits, and safety initiatives in a regulated environment.

Practical notes

This is a full-time onsite role based in San Francisco.

Hours are aligned with standard business operations, with availability for occasional after-hours or weekend support as needed for events, deliveries, or safety procedures.

Travel is not required for this role.

Visa sponsorship is not available for this position.

Candidates must be authorized to work in the United States without sponsorship.

Deadlines are not specified in this job description; applications will be reviewed on a rolling basis until the position is filled.