Scientist, Hematopoiesis
Job description
About the role
In this role, you will own the full lifecycle of HSC therapeutic development from initial sample intake through final process validation. You will leverage deep hematopoietic knowledge to design experiments that test the boundaries of cellular reprogramming and autophagy in tissue regeneration. A core part of your ownership involves building robust differentiation protocols that are both scientifically rigorous and technically scalable for future manufacturing. You will be responsible for establishing quality control frameworks that ensure every iteration of our research meets strict standards for integrity and reproducibility. Collaboration will be a daily focus as you integrate input from bench biologists, computational biologists, and logistics experts to keep the project moving forward. You will maintain a mindset of rapid iteration, constantly refining methods based on data while keeping the mission of extending human healthspan at the center of your decisions. This position requires a mission-driven individual who is adaptable, meticulous, and motivated to work at the forefront of aging research. You will take ownership of documenting every step so that current work lays a solid foundation for future automation and scaling efforts.
Key facts
What you'll do
- Design and implement intake procedures for cellular sample collection with rigorous tracking to support aging-related experiments and long-term study integrity.
- Construct and refine differentiation protocols by applying principles from cellular reprogramming and autophagy to enhance tissue performance and biological optimization.
- Analyze quality control metrics to verify data integrity, reproducibility, and consistency across iterative cycles of experimentation and process development.
- Develop scalable manufacturing methods designed for reliable protocol execution, aiming to create processes that produce consistent outputs and support future expansion.
- Partner closely with computational biologists and bench scientists to align operational logistics across all departments involved in the project and ensure seamless integration of workflows.
- Establish clear and transparent communication channels so that hypotheses, results, and project changes are understood by specialists from diverse scientific and logistical backgrounds.
- Adapt quickly to new scientific information while maintaining strict focus on mission objectives, ensuring that priorities align with the primary goals of extending human healthspan.
- Define and document detailed process standards for every step of hematopoiesis workflows to facilitate future automation, validation, and long-term scaling efforts.
- Lead experiments that probe the boundaries of HSC differentiation and maturation, using innovative methods to improve yield, purity, and functional outcomes.
- Troubleshoot unexpected results in differentiation protocols by applying a systematic approach to identify variables and implement corrective actions efficiently.
- Maintain meticulous records of all experimental conditions, observations, and modifications to support traceability and enable replication of successful methods.
- Contribute to cross-functional discussions by translating complex hematopoietic concepts into clear insights for team members with varied expertise.
- Support the evaluation of new protocols against predefined success metrics, providing data-driven recommendations for optimization and scaling.
- Act as a technical owner for hematopoiesis-related projects, ensuring that scientific questions are answered thoroughly and results are communicated effectively to stakeholders.
Requirements
- You must possess deep expertise in hematopoiesis that directly guides protocol decisions and the design of experiments related to HSC biology.
- You must have experience optimizing complex workflows, balancing high speed with meticulous accuracy in a fast-paced startup environment.
- You must organize details in a clear manner to enable transparent collaboration between laboratory personnel and computational staff.
- You must be able to iterate rapidly, including reprioritizing tasks when scientific requirements demand it over team preferences or personal convenience.
- You must approach learning with a can-do attitude and a hands-on methodology, embracing new techniques and technologies as they emerge.
- You must take pride in maintaining the highest standards while continuously improving research practices for both speed and precision.
- You must communicate clearly with professionals from varied fields, including bench biologists, quality control scientists, and logistics experts.
- Adaptability is essential, as you will quickly adjust priorities based on a hierarchy where the mission precedes the team and the individual.
- You must be motivated to work at the forefront of science and contribute to extending the human healthspan through innovative therapeutic research.
- You must be located in Redwood City, California, as this role requires in-person collaboration within our laboratory setting.
- You must be authorized to work in the United States without sponsorship for this position at this time.
- You must commit to full-time engagement during regular business hours to ensure alignment with team activities and project timelines.
- You must meet the start date outlined in the official offer once the hiring process is completed.
- You must adhere to all internal quality standards and documentation practices required for regulated biotechnology research.
Nice to have
There are no specific nice-to-have qualifications or additional skills listed for this position. Please confirm application details on the official page.
Practical notes
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Location: This role is based in Redwood City, California, and requires in-person presence.
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Engagement: Full-time commitment is required for this position.
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Compensation: The salary for this role is $180,000 annually.
- Travel: There are no specific travel requirements mentioned for this role.
- Visa: Sponsorship is not available for this position at this time.
- Hours: Standard full-time hours are expected.
- Deadlines: Please confirm application details and start date requirements on the official page.