Senior Electrical Engineer, PCB Systems

About the role

Flagship Pioneering, Inc. is seeking a Senior Electrical Engineer, PCB Systems to join their growing team in Cambridge, Massachusetts. This role centers on the design and development of printed circuit board systems that form the foundation of hardware solutions for life sciences ventures. The engineer will work within a venture creation environment where electronic systems are conceived, built, and refined to support innovative biotechnology and healthcare companies. The position demands close collaboration with cross-functional teams to define, prototype, and refine PCB architectures from initial concept through final production, ensuring that each design meets the rigorous standards of the life sciences industry. The engineer will have the opportunity to work on diverse hardware challenges across multiple venture stages.

Key facts

This role is part of the core engineering organization at Flagship Pioneering, Inc., where hardware development efforts directly support the company's mission of creating and nurturing life sciences ventures from the ground up. The position is headquartered in Cambridge, Massachusetts, at the center of one of the world's most active biotechnology and innovation ecosystems. The engineer will contribute to projects that span early-stage concept exploration through to production-ready hardware deliverables for portfolio companies. The work involves both individual contribution and team-based problem-solving in a collaborative, fast-moving environment.

What you'll do

Design and develop printed circuit board layouts for life sciences hardware applications and systems

Create system-level electrical architectures that meet detailed product specifications and performance targets

Work closely with mechanical and software engineers to integrate PCB designs into larger embedded systems

Perform thorough signal integrity and power integrity analysis on complex circuit board designs

Select appropriate electronic components and materials for PCB fabrication, assembly, and testing processes

Develop and maintain comprehensive design documentation including schematics, layouts, and bill of materials

Conduct design reviews and provide technical guidance to junior engineering staff members

Iterate on hardware prototypes, diagnosing and resolving electrical issues during rigorous testing phases

Ensure all designs comply with relevant industry standards for safety, reliability, and manufacturing

Collaborate with portfolio company teams to understand their hardware requirements and deliver effective solutions

Evaluate and recommend new PCB materials and manufacturing processes to improve product quality

Manage design revisions and maintain version control across multiple hardware project streams

Requirements

Demonstrated experience in electrical engineering with a strong focus on printed circuit board design and development

Strong understanding of analog and digital circuit principles applied to practical system-level design work

Proficiency with PCB design software and electronic design automation tools is expected and valued

Ability to read and interpret technical datasheets, reference designs, and complex application notes accurately

Experience managing multiple hardware projects simultaneously in a fast-paced and demanding work environment

Bachelor's degree or higher in electrical engineering or a closely related technical field

Effective written and verbal communication skills for working with both technical and non-technical stakeholders

A self-directed approach to problem-solving with consistent attention to detail, quality, and thorough documentation

Familiarity with industry standards such as IPC specifications for printed circuit board manufacturing

Track record of delivering reliable hardware designs on schedule within regulated or quality-focused environments

Nice to have

Familiarity with high-speed digital design and advanced signal integrity techniques for printed circuit board systems

Experience working in a venture capital or startup incubation environment is highly valued

Knowledge of regulatory standards relevant to medical or life science device products and processes

Background in both hardware development and software integration workflows is considered a strong plus

Prior experience with rapid prototyping methods and iterative design validation in a laboratory setting

Skills & tools

Printed circuit board design and layout software for schematic and layout creation

Electronic design automation and schematic capture tools for circuit design workflows

Signal integrity and power integrity simulation software for board-level analysis

Hardware debugging and measurement instruments such as oscilloscopes and logic analyzers

Version control systems for managing hardware design files and revisions

Technical documentation and specification writing platforms for design record keeping

Printed circuit board fabrication and assembly process knowledge including Gerber file generation

Practical notes

This position is based in Cambridge, Massachusetts, and requires regular on-site presence at the company office

The role reports directly to senior engineering leadership within the Flagship Pioneering organizational structure

Candidates should expect to work closely alongside venture teams and portfolio company engineering groups regularly

The hiring process includes technical interviews focused on PCB design principles and systems-level thinking abilities

Flagship Pioneering, Inc. is an equal opportunity employer and welcomes applicants from diverse backgrounds and experiences