Sr. Clinical Trial Manager

About the role

Bamboohr is seeking a Senior Clinical Trial Manager to lead and oversee clinical trial operations within the organization. This role is based in South San Francisco, California, and is a full-time position. The manager will coordinate cross-functional teams to ensure trials are executed efficiently and in compliance with regulatory standards, serving as a primary point of contact for sponsors and investigators. The position involves planning, monitoring, and closing clinical studies from start to finish while advancing Bamboohr's mission to bring genomic insights into clinical care.

Key facts

What you'll do

Lead the planning and execution of clinical trials across multiple study sites and therapeutic areas.

Coordinate with internal stakeholders and external partners to align trial protocols, timelines, and deliverables.

Monitor trial progress and ensure adherence to established budgets, schedules, and quality standards throughout each phase.

Prepare and review regulatory submissions, including ethics committee and institutional review board documentation for trial approval.

Manage relationships with contract research organizations and investigative sites to ensure smooth trial operations.

Track and report key trial metrics, milestones, and deliverables to senior leadership and external sponsors regularly.

Ensure all clinical activities comply with applicable regulations, guidelines, and standard operating procedures at every stage.

Oversee the collection, validation, and integrity of clinical data generated during study conduct and monitoring visits.

Support the development of clinical study protocols, investigator brochures, and related trial documents from initial drafts.

Identify risks and implement mitigation strategies to keep trials on track, within scope, and well documented.

Facilitate communication between medical, regulatory, and operations teams during all trial phases and milestone reviews.

Lead post-trial activities including close-out visits, final report preparation, and comprehensive lessons-learned documentation for future reference.

Collaborate with the clinical operations team to develop risk-based monitoring plans and site selection criteria.

Drive continuous improvement in trial processes by evaluating workflows and recommending operational enhancements to leadership.

Requirements

Bachelor's degree in a life science, clinical research, or related field is required for this position.

A minimum of seven years of experience in clinical trial management or a closely related discipline.

Demonstrated experience managing multiple concurrent clinical trials from initiation through closeout with successful outcomes.

Strong knowledge of Good Clinical Practice guidelines and applicable regulatory frameworks governing human subject research.

Proven ability to manage cross-functional teams and external vendors in a fast-paced, deadline-driven environment.

Experience with clinical trial budgeting, forecasting, and resource allocation across multiple study sites simultaneously.

Excellent written and verbal communication skills for engaging with diverse stakeholders at all organizational levels.

Ability to travel to clinical sites and sponsor meetings as needed throughout the calendar year.

Nice to have

Master's degree in clinical research, public health, or a related scientific discipline is preferred.

Prior experience working within the genomics or precision medicine sector in a clinical setting.

Familiarity with electronic data capture systems and clinical trial management software platforms used in industry.

Certification from a recognized clinical research organization such as ACRP or SOCRA is a plus.

Knowledge of health economics and outcomes research methodologies applied in clinical development programs.

Skills & tools

Clinical trial management processes and study start-up procedures across multiple phases of development.

Regulatory submission preparation and compliance tracking for all phases of clinical studies and audits.

Budget development, monitoring, and variance analysis for clinical trial financial management and reporting.

Stakeholder management and cross-functional coordination between internal teams and external research partners.

GCP and ICH guideline knowledge with practical application in clinical trial settings.

Project management methodologies and timeline tracking to ensure study milestone delivery and reporting.

Practical notes

This is a full-time, on-site position located in South San Francisco, California, requiring daily presence.

The role requires regular interaction with clinical sites, sponsors, and internal teams across multiple time zones.

Candidates should be prepared for a dynamic work environment with shifting priorities and tight regulatory deadlines.

The hiring process includes multiple interview rounds and may involve a case study or presentation component.

About the company

Medicine is our platform. Accessibility is our cure.