Member of Research Staff, Preclinical

About the role

The is a hands-on technical role focused on the execution and support of in vivo studies. On this team, you will ensure animal studies and testing proceed without interruption by maintaining rigorous operational continuity. You will follow protocols and regulatory expectations with precision to keep experiments on schedule and compliant. This position requires you to apply high integrity and strong professional judgment in all decision points that affect data quality and animal welfare. You will maintain detailed lab books or version-controlled analysis code to guarantee traceability and reproducibility of all procedures. Additionally, you will build fixtures and adapt equipment to keep workflows running smoothly in a rapidly evolving research environment. You will address practical problems in real time to support uninterrupted workflows across the preclinical pipeline. This role is embedded within a mission-driven team developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth.

Key facts

What you'll do

• You will ensure animal studies and testing proceed without interruption by coordinating schedules, monitoring subjects, and maintaining facility readiness.
• You will follow protocols and regulatory expectations with meticulous attention to detail, documenting every step to satisfy compliance and audit requirements.
• You will apply high integrity and strong professional judgment when troubleshooting unexpected variables that could impact study outcomes or safety.
• You will maintain detailed lab books or version-controlled analysis code to create a clear, searchable record of procedures, observations, and modifications.
• You will build fixtures and adapt equipment to keep workflows running, modifying hardware or software tools to meet experimental demands.
• You will address practical problems to support uninterrupted workflows, diagnosing bottlenecks and implementing immediate corrective actions in the lab.
• You will perform dosing, anesthesia, perfusion, and tissue harvest with precision, ensuring consistency across biological replicates and study phases.
• You will handle rodents and perform essential procedural tasks, including routine monitoring, handling, and husbandry activities.
• You will carry out stereotactic viral injections when experience exists, targeting specific brain regions with accuracy and reproducibility.
• You will perform cranial window implantations when experience exists, supporting chronic imaging and recording studies.
• You will use sterile cell culture technique to maintain reagents, viral vectors, or tissue samples under clean conditions.
• You will solve practical problems as part of standard lab work, innovating within constraints to preserve data quality and animal well-being.

Requirements

• You need hands-on experience in a preclinical or animal research laboratory, demonstrating consistent competence in live animal studies.
• You need neuroscience experience preferred, with a foundational understanding of brain circuits, behavior, and experimental models.
• You need handling rodents, including experience with multiple strains, sexes, and age ranges under varying experimental conditions.
• You need performing dosing, anesthesia, perfusion, and tissue harvest, showing proficiency across multiple species and procedures.
• You need familiarity with sterile cell culture technique, maintaining aseptic practices for cell lines, viruses, or explants.
• You need a bachelor's, master's, or PhD in neuroscience, biology, or related field (preferred), with evidence of sustained laboratory responsibility.
• You need the ability to work independently and in collaboration, communicating clearly with engineers, scientists, and animal facility staff.
• You need strict adherence to institutional animal care and use committee standards, ensuring that all work remains within approved protocols.

Nice to have

• It helps if you have experience with stereotactic viral injections, including coordination, calibration, and post-procedure monitoring.
• It helps if you have performed cranial window implantations, managing long-term preparations and troubleshooting complications.

Practical notes

Note: not stated. Note: not stated. Note: About the company

At Nudge, our mission is to develop the best technology for interfacing with the brain to improve people's lives. We're starting with an approach that we believe can help the most people the fastest, and also allow us to learn as much about the brain as possible: developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth.

For , Ensure animal studies and testing proceed without interruption.

For , Follow protocols and regulatory expectations.

For , Apply high integrity and strong professional judgment.

For , Maintain detailed lab books or version-controlled analysis code.

For , Build fixtures and adapt equipment to keep workflows running.

For , Address practical problems to support uninterrupted workflows.

For , Perform dosing, anesthesia, perfusion, and tissue harvest.

For , Handle rodents and perform essential procedural tasks.

For , Carry out stereotactic viral injections when experience exists.

For , Perform cranial window implantations when experience exists.

For , Use sterile cell culture technique.

For , Solve practical problems as part of standard lab work.