Senior Scientist, R&D

About the role

Hims and Hers is hiring a Senior Scientist to join the LABS team in an individual contributor capacity. You will report to the Director of R&D to lead the development and validation of diagnostic assays for both traditional and at-home testing initiatives. This is an on-site laboratory position focused on taking projects from initial feasibility through to clinical implementation.

Key facts

What you'll do

• Design and execute immunoassay studies including ELISA, chemiluminescent, and multiplex formats.
• Conduct method validation for precision, accuracy, linearity, interference, and stability.
• Apply statistical methodologies and Design of Experiments (DOE) to optimize assays and troubleshoot performance.
• Develop and validate LC-MS/MS methods for hormone and clinical chemistry analytes.
• Create and update SOPs to maintain reproducible laboratory standards.
• Process biological matrices including serum, plasma, and whole blood collected via at-home devices like Tasso and YourBio Health.
• Operate and maintain SCIEX 4500MD or equivalent mass spectrometry systems.
• Support high-throughput workflows on Roche Cobas Pro, Sysmex, and liquid handling automation platforms.
• Analyze experimental data to calculate total allowable error, bias, and precision.
• Collaborate with the Quality team to ensure compliance with CLIA and CAP standards.

Requirements

• PhD in Biochemistry, Clinical Chemistry, Molecular Biology, Analytical Chemistry, or related field with 4+ years of experience; OR Master's degree with 7+ years; OR Bachelor's degree with 10+ years of relevant bench experience.
• Hands-on background in immunoassay development.
• Experience with LC-MS/MS sample preparation and method validation.
• Experience working with both capillary and venous blood specimens.
• Proven track record of leading verification and validation studies.
• Proficiency in applying DOE and statistical tools to laboratory development.

Nice to have

• Experience in CAP or CLIA regulated laboratory environments.
• Background in at-home or point-of-care diagnostic programs.
• Familiarity with dried blood spot (DBS) workflows and stability testing.
• Knowledge of biomarker categories related to longevity, metabolic health, and consumer wellness.
• Experience with NGS library preparation and bioinformatics data review.

Skills & tools

• Immunoassay (ELISA, chemiluminescent, multiplex)
• LC-MS/MS (SCIEX 4500MD)
• Clinical chemistry and hematology platforms (Roche Cobas Pro, Sysmex)
• Liquid handling automation
• Statistical analysis and DOE
• SOP development and regulatory documentation

Practical notes

• Benefits include medical, dental, and vision insurance, 401k with employer match, unlimited PTO, quarterly mental health days, and an Employee Stock Purchase Program.
• The company provides reasonable accommodations for individuals with disabilities during the application process; requests can be directed to accommodations@forhims.com.
• This role is strictly on-site in New Jersey.